College football picks will make a play on the Oregon Ducks -4 1/2 against the Ohio St Buckeyes. The Oregon speed on offense will be diffficult to contain for the Ohio St Buckeyes in this contest. Ohio St suffered a home loss to the down USC Trojans with an immobile freshman quarterbac at the helm. The difference in this game will be the experience and dual run/pass threat at quarterback for Oregon in Jeremiah Masoli. This Oregon spread attack will be too much for this Big 10 team to contend with. We saw what Florida did to the Buckeyes last year. Take Oregon.
College football picks plays on Oregon Ducks -4 1/2
College football picks handicapped by Tonys Picks







































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